Cytoskeleton in Construction and Operation of Neural Circuits

Topic
This article lists and discusses items about the role of cytoskeleton in constructing and operating neural circuits.

Particularly Relevant Items
Purves, D., Augustine, G.J., Fitzpatrick, D., Hall, W.C., LaMantia, A.-S., McNamara, J.O., and White, L.E., Eds., Neuroscience, Fourth Edition, Sunderland, Mass.: Sinauer Associates, 2008: Purves, D., Augustine, G.J., Fitzpatrick, D., Hall, W.C., LaMantia, A.-S., and White, L.E., Eds., Neuroscience, Fifrth Edition, Sunderland, Mass.: Sinauer Associates, 2012 is highly similar to the Fourth Edition cited above, but with a relevant change in one chapter's title:
 * At pages 11-13, a section headed "Neural Circuits" explains that, rather than functioning in isolation, neurons in ensembles process information, providing the basis of sensation, perception, and behavior.
 * Chapter 23, "Construction of Neural Circuits", pages 577-609, describes roles of cytoskeleton in constructing neural circuits, including axon growth cone motility and synapse formation.
 * Chapter 24, "Modification of Neural Circuits as a Result of Experience", pages 537-557, describes [COMPLETE THIS]

Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., and Walter, P., Molecular Biology of the Cell, Fifth Edition, New York: Garland Science, 2008:
 * Pages 1047-1050 describe roles of cytoskeleton in neurons, mentioning, e.g., that microtubules in axons act as a highway to transport proteins, vesicles, etc. to axon terminals, that growth cones (both on axons and dendrites) are rich in actin, and that neuronal morphology undergoes actin-dependent rearrangement.

Possibly Relevant Items
Baas, P.W., Myers, K.A., Qiang, L., and Nadar, V.C., "Microtubules: Organization and Function in Neurons", in Squire, L.R., Ed.-in-Chief, Encyclopedia of Neuroscience, Elsevier, 2009, pp. 871-878:
 * Page 871: Microtubules are particularly important for architecture of axons and dendrites and for specific and directional transport of proteins and organelles within these processes. Microtubules are also, of course, the filaments comprising the mitotic spindle during cell division, but are extremely abundant in neurons even though terminally postmitotic, i.e. no longer for spindles. Microtubules are critically important for migration of cell body and cue-dependent pathfinding of growth cone at axon tip.
 * Page 872: In axons, microtubule plus ends are away from the cell body, but in dendrites, roughly equal numbers of microtubules have plus ends directed away from and toward the cell body. Another, compositional difference is that microtubule-associated proteins (MAPs) of different types decorate microtubules, e.g. tau is present in axons and MAP2 is present in dendrites.
 * Page 875: Dendritic transport is probably more complex than axonal transport because of opposite polarities of dendritic microtubules.
 * Page 878 explains that, in addition to being structural, microtubules are highly dynamic and can interact with regulatory proteins. They participate in, e.g., transduction of forces in neuronal migration and growth cone guidance.